Soft Tissue Sarcoma
Literature Analysis
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Clicking on the Gene or Topic will take you to a separate more detailed page. Sort this list by clicking on a column heading e.g. 'Gene' or 'Topic'.
Gene | Location | Aliases | Notes | Topic | Papers |
EWSR1 | 22q12.2 | EWS, EWS-FLI1, bK984G1.4 | -EWSR1 and Soft Tissue Sarcoma | 356 | |
CD34 | 1q32.2 | -CD34 and Soft Tissue Sarcoma | 212 | ||
KIT | 4q12 | PBT, SCFR, C-Kit, CD117 | -KIT and Soft Tissue Sarcoma | 208 | |
PTEN | 10q23.31 | BZS, DEC, CWS1, GLM2, MHAM, TEP1, MMAC1, PTEN1, 10q23del | -PTEN and Soft Tissue Sarcoma | 83 | |
BCOR | Xp11.4 | MAA2, ANOP2, MCOPS2 | -BCOR and Soft Tissue Sarcoma | 71 | |
SMARCB1 | 22q11.23 | RDT, CSS3, INI1, SNF5, Snr1, BAF47, MRD15, RTPS1, Sfh1p, hSNFS, SNF5L1, SWNTS1, PPP1R144 | -SMARCB1 and Soft Tissue Sarcoma | 70 | |
DDIT3 | 12q13.3 | CHOP, CEBPZ, CHOP10, CHOP-10, GADD153 | Translocation | -t(12;16)(q13;p11) FUS-DDIT3 in Mixoid Liposarcoma -DDIT3 and Soft Tissue Cancers | 39 |
AKT1 | 14q32.33 | AKT, PKB, RAC, CWS6, PRKBA, PKB-ALPHA, RAC-ALPHA | -AKT1 and Sarcoma | 53 | |
PDGFRB | 5q32 | IMF1, KOGS, IBGC4, JTK12, PDGFR, PENTT, CD140B, PDGFR1, PDGFR-1 | -PDGFRB and Soft Tissue Sarcoma | 46 | |
CD99 | Xp22.33 and Yp11.2 | MIC2, HBA71, MIC2X, MIC2Y, MSK5X | -CD99 and Soft Tissue Cancers | 43 | |
SLC2A1 | 1p34.2 | CSE, PED, DYT9, GLUT, DYT17, DYT18, EIG12, GLUT1, HTLVR, GLUT-1, SDCHCN, GLUT1DS | -GLUT1 expression in Soft Tissue Sarcoma | 42 | |
PIK3CA | 3q26.32 | MCM, CWS5, MCAP, PI3K, CLOVE, MCMTC, PI3K-alpha, p110-alpha | -PIK3CA and Soft Tissue Sarcoma | 42 | |
FUS | 16p11.2 | TLS, ALS6, ETM4, FUS1, POMP75, HNRNPP2 | Translocation | -t(12;16)(q13;p11) FUS-DDIT3 in Mixoid Liposarcoma -t(7;16)(q33;p11) FUS-CREB3L2 in Low-grade fibromyxoid sarcoma | 39 |
JAZF1 | 7p15.2-p15.1 | TIP27, ZNF802 | -JAZF1 and Soft Tissue Sarcoma | 38 | |
PAX3 | 2q35 | WS1, WS3, CDHS, HUP2 | -PAX3 and Soft Tissue Cancers | 36 | |
ATF1 | 12q13.12 | TREB36, EWS-ATF1, FUS/ATF-1 | -ATF1 and Soft Tissue Cancers | 32 | |
MSH2 | 2p21 | FCC1, COCA1, HNPCC, LCFS2, HNPCC1 | -MSH2 and Soft Tissue Sarcoma | 28 | |
TOP1 | 20q12 | TOPI | -TOP1 and Soft Tissue Sarcoma | 27 | |
MYOG | 1q32.1 | MYF4, myf-4, bHLHc3 | -MYOG and Soft Tissue Sarcoma | 25 | |
MDM4 | 1q32.1 | HDMX, MDMX, MRP1 | -MDM4 and Soft Tissue Sarcoma | 24 | |
PAX7 | 1p36.13 | HUP1, RMS2, PAX7B | -PAX7 and Soft Tissue Cancers | 23 | |
NKX2-2 | 20p11.22 | NKX2B, NKX2.2 | -NKX2-2 and Soft Tissue Sarcoma | 18 | |
ERG | 21q22.2 | p55, erg-3 | -ERG and Soft Tissue Cancers | 17 | |
ETV6 | 12p13.2 | TEL, THC5, TEL/ABL | -ETV6 and Soft Tissue Cancers | 17 | |
NR4A3 | 9q31.1 | CHN, TEC, CSMF, NOR1, MINOR | -NR4A3 and Soft Tissue Cancers | 16 | |
MYB | 6q23.3 | efg, Cmyb, c-myb, c-myb_CDS | -MYB and Soft Tissue Sarcoma | 16 | |
MET | 7q31.2 | HGFR, AUTS9, RCCP2, c-Met, DFNB97 | -C-MET and Soft Tissue Cancers | 16 | |
TSPAN31 | 12q13.3 | SAS | -TSPAN31 and Soft Tissue Sarcoma | 15 | |
CREB3L2 | 7q33 | BBF2H7 | Translocation | -t(7;16)(q33;p11) FUS-CREB3L2 in Low-grade fibromyxoid sarcoma -CREB3L2 and Soft Tissue Cancers | 14 |
MYOD1 | 11p15.1 | PUM, MYF3, MYOD, bHLHc1 | -MYOD1 and Soft Tissue Cancers | 14 | |
CIC | 19q13.2 | -CIC and Soft Tissue Cancers | 12 | ||
DUX4L1 | 4q35.2 | DUX4, DUX10 | -DUX4 and Soft Tissue Cancers | 11 | |
PTER | 10p13 | HPHRP, RPR-1 | -PTER and Soft Tissue Cancers | 11 | |
S100A6 | 1q21.3 | 2A9, PRA, 5B10, CABP, CACY, S10A6 | -S100A6 and Soft Tissue Sarcoma | 10 | |
MUC4 | 3q29 | ASGP, MUC-4, HSA276359 | -MUC4 and Soft Tissue Cancers | 10 | |
CREB1 | 2q34 | CREB | -CREB1 and Soft Tissue Cancers | 9 | |
CTAG1B | Xq28 | CTAG, ESO1, CT6.1, CTAG1, LAGE-2, LAGE2B, NY-ESO-1 | -CTAG1B and Soft Tissue Sarcoma | 9 | |
TGFBR3 | 1p22.1 | BGCAN, betaglycan | -TGFBR3 and Soft Tissue Cancers | 9 | |
ASPSCR1 | 17q25.3 | TUG, ASPL, ASPS, RCC17, UBXD9, UBXN9, ASPCR1 | Translocation | -der(17)t(X;17)(p11.2;q25) in Alveolar Soft-Part Sarcoma -ASPSCR1 and Soft Tissue Cancers | 8 |
TFG | 3q12.2 | TF6, HMSNP, SPG57, TRKT3 | -TFG and Soft Tissue Sarcoma | 8 | |
OSCAR | 19q13.42 | PIGR3, PIgR-3 | -OSCAR and Soft Tissue Sarcoma | 8 | |
TCF12 | 15q21.3 | HEB, CRS3, HTF4, TCF-12, bHLHb20, HsT17266 | -TCF12 and Soft Tissue Sarcoma | 8 | |
GNAS | 20q13.32 | AHO, GSA, GSP, POH, GPSA, NESP, SCG6, SgVI, GNAS1, PITA3, C20orf45 | -GNAS and Soft Tissue Cancers | 8 | |
HMGA1 | 6p21.31 | HMG-R, HMGIY, HMGA1A | -HMGA1 and Soft Tissue Cancers | 7 | |
CREB3L1 | 11p11.2 | OASIS | -CREB3L1 and Soft Tissue Cancers | 7 | |
CYP3A4 | 7q22.1 | HLP, CP33, CP34, CYP3A, NF-25, CYP3A3, P450C3, CYPIIIA3, CYPIIIA4, P450PCN1 | -CYP3A4 and Soft Tissue Sarcoma | 6 | |
CKAP4 | 12q23.3 | p63, CLIMP-63, ERGIC-63 | -CKAP4 and Soft Tissue Sarcoma | 6 | |
NCOA2 | 8q13.3 | SRC2, TIF2, GRIP1, KAT13C, NCoA-2, bHLHe75 | -NCOA2 and Soft Tissue Cancers | 6 | |
CYP3A5 | 7q22.1 | CP35, PCN3, CYPIIIA5, P450PCN3 | -CYP3A5 and Soft Tissue Sarcoma | 6 | |
YEATS4 | 12q15 | YAF9, GAS41, NUBI-1, 4930573H17Rik, B230215M10Rik | -YEATS4 and Soft Tissue Sarcoma | 6 | |
CD163 | 12p13.3 | M130, MM130 | -CD163 and Soft Tissue Sarcoma | 6 | |
MAGEA3 | Xq28 | HIP8, HYPD, CT1.3, MAGE3, MAGEA6 | -MAGEA3 and Soft Tissue Sarcoma | 6 | |
FLT4 | 5q35.3 | PCL, FLT-4, FLT41, LMPH1A, VEGFR3, VEGFR-3 | -FLT4 and Soft Tissue Sarcoma | 6 | |
LATS1 | 6q25.1 | wts, WARTS | -LATS1 and Soft Tissue Sarcoma | 6 | |
MGEA5 | 10q24.32 | OGA, MEA5, NCOAT | -MGEA5 and Soft Tissue Cancers | 5 | |
TLE1 | 9q21.32 | ESG, ESG1, GRG1 | -TLE1 and Soft Tissue Cancers | 5 | |
DAPK2 | 15q22.31 | DRP1, DRP-1 | -DAPK2 and Soft Tissue Cancers | 4 | |
TAF15 | 17q12 | Npl3, RBP56, TAF2N, TAFII68 | -TAF15 and Soft Tissue Cancers | 4 | |
PTPRD | 9p24.1-p23 | HPTP, PTPD, HPTPD, HPTPDELTA, RPTPDELTA | -PTPRD and Soft Tissue Sarcoma | 4 | |
MED12 | Xq13.1 | OKS, FGS1, HOPA, OPA1, OHDOX, ARC240, CAGH45, MED12S, TNRC11, TRAP230 | -MED12 and Soft Tissue Cancers | 4 | |
EZH2 | 7q36.1 | WVS, ENX1, EZH1, KMT6, WVS2, ENX-1, EZH2b, KMT6A | -EZH2 and Soft Tissue Cancers | 4 | |
TOP2A | 17q21.2 | TOP2, TP2A | -TOP2A and Soft Tissue Sarcoma | 4 | |
PATZ1 | 22q12.2 | ZSG, MAZR, PATZ, RIAZ, ZBTB19, ZNF278, dJ400N23 | -PATZ1 and Soft Tissue Sarcoma | 4 | |
LMNA | 1q22 | FPL, IDC, LFP, CDDC, EMD2, FPLD, HGPS, LDP1, LMN1, LMNC, MADA, PRO1, CDCD1, CMD1A, FPLD2, LMNL1, CMT2B1, LGMD1B | -LMNA and Soft Tissue Cancers | 3 | |
CD1A | 1q23.1 | R4, T6, CD1, FCB6, HTA1 | -CD1A and Soft Tissue Sarcoma | 3 | |
CAMTA1 | 1p36.31-p36.23 | CANPMR | -CAMTA1 and Soft Tissue Cancers | 3 | |
WWTR1 | 3q25.1 | TAZ | -WWTR1 and Soft Tissue Cancers | 3 | |
COL1A1 | 17q21.33 | OI1, OI2, OI3, OI4, EDSC | -COL1A1 and Soft Tissue Cancers | 3 | |
NNAT | 20q11.23 | Peg5 | -NNAT and Soft Tissue Sarcoma | 3 | |
GAPDH | 12p13.31 | G3PD, GAPD, HEL-S-162eP | -GAPDH and Soft Tissue Cancers | 3 | |
MIF | 22q11.23 | GIF, GLIF, MMIF | -MIF and Soft Tissue Cancers | 2 | |
DAPK1 | 9q21.33 | DAPK | -DAPK1 and Soft Tissue Cancers | 2 | |
CDKN1B | 12p13.1 | KIP1, MEN4, CDKN4, MEN1B, P27KIP1 | Prognostic | -CDKN1B Expression and Survival in Liposarcoma | 2 |
SRSF3 | 6p21.31-p21.2 | SFRS3, SRp20 | -SRSF3 and Soft Tissue Sarcoma | 2 | |
TIMP3 | 22q12.3 | SFD, K222, K222TA2, HSMRK222 | -TIMP3 and Soft Tissue Cancers | 2 | |
ATF6 | 1q23.3 | ACHM7, ATF6A | -ATF6 and Soft Tissue Sarcoma | 2 | |
SSTR1 | 14q21.1 | SS1R, SS1-R, SRIF-2, SS-1-R | -SSTR1 and Soft Tissue Cancers | 2 | |
TUSC2 | 3p21.31 | PAP, FUS1, PDAP2, C3orf11 | -TUSC2 and Soft Tissue Sarcoma | 2 | |
RANBP2 | 2q12.3 | ANE1, TRP1, TRP2, ADANE, IIAE3, NUP358 | -RANBP2 and Soft Tissue Sarcoma | 2 | |
PTPRC | 1q31.3-q32.1 | LCA, LY5, B220, CD45, L-CA, T200, CD45R, GP180 | -PTPRC and Soft Tissue Sarcoma | 2 | |
ICAM1 | 19p13.2 | BB2, CD54, P3.58 | -ICAM1 and Soft Tissue Cancers | 2 | |
MAP2K4 | 17p12 | JNKK, MEK4, MKK4, SEK1, SKK1, JNKK1, SERK1, MAPKK4, PRKMK4, SAPKK1, SAPKK-1 | -MAP2K4 and Soft Tissue Cancers | 2 | |
TPTE | 21p11.2 | CT44, PTEN2 | -TPTE and Soft Tissue Cancers | 2 | |
MMP9 | 20q13.12 | GELB, CLG4B, MMP-9, MANDP2 | -MMP9 and Soft Tissue Cancers | 2 | |
FHIT | 3p14.2 | FRA3B, AP3Aase | -FHIT and Soft Tissue Cancers | 2 | |
GSTA1 | 6p12.2 | GST2, GTH1, GSTA1-1, GST-epsilon | -GSTA1 and Soft Tissue Sarcoma | 2 | |
AREG | 4q13.3 | AR, SDGF, AREGB, CRDGF | -AREG and Soft Tissue Cancers | 1 | |
FOXL2 | 3q22.3 | BPES, PFRK, POF3, BPES1, PINTO | -FOXL2 and Soft Tissue Sarcoma | 1 | |
ACVRL1 | 12q13.13 | HHT, ALK1, HHT2, ORW2, SKR3, ALK-1, TSR-I, ACVRLK1 | -ACVRL1 and Soft Tissue Cancers | 1 | |
PTPRF | 1p34.2 | LAR, BNAH2 | -PTPRF and Soft Tissue Sarcoma | 1 | |
FGF23 | 12p13.32 | ADHR, FGFN, HYPF, HPDR2, PHPTC | -FGF23 and Soft Tissue Cancers | 1 | |
ANO1 | 11q13.3 | DOG1, TAOS2, ORAOV2, TMEM16A | -ANO1 and Soft Tissue Cancers | 1 | |
CHIA | 1p13.2 | CHIT2, AMCASE, TSA1902 | -CHIA and Soft Tissue Cancers | 1 | |
IL2RB | 22q12.3 | CD122, IMD63, IL15RB, P70-75 | -IL2RB and Soft Tissue Cancers | 1 | |
LDHA | 11p15.1 | LDHM, GSD11, PIG19, HEL-S-133P | -LDHA and Soft Tissue Cancers | 1 | |
SSX1 | Xp11.23 | SSRC, CT5.1 | Translocation | -t(X;18)(p11.2;q11.2) SS18-SSX1 in Synovial Sarcoma | |
TFE3 | Xp11.23 | TFEA, RCCP2, RCCX1, bHLHe33 | Translocation | -der(17)t(X;17)(p11.2;q25) in Alveolar Soft-Part Sarcoma | |
SSX2 | Xp11.22 | SSX, HD21, CT5.2, CT5.2A, HOM-MEL-40 | Translocation | -t(X;18)(p11.2;q11.2) SS18-SSX2 in Synovial Sarcoma | |
SSX4 | Xp11.23 | CT5.4 | Translocation | -t(X;18)(p11.2;q11.2) SS18-SSX4 in Synovial Sarcoma | |
SS18 | 18q11.2 | SYT, SSXT | Translocation | -t(X;18)(p11.2;q11.2) SS18-SSX1 in Synovial Sarcoma -t(X;18)(p11.2;q11.2) SS18-SSX2 in Synovial Sarcoma -t(X;18)(p11.2;q11.2) SS18-SSX4 in Synovial Sarcoma |
Note: list is not exhaustive. Number of papers are based on searches of PubMed (click on topic title for arbitrary criteria used).
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Cite this page: Cotterill SJ. Soft Tissue Sarcoma, Cancer Genetics Web: http://www.cancer-genetics.org/X2003.htm Accessed:
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