Soft Tissue Sarcoma

Overview

Literature Analysis

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Tag cloud generated 29 August, 2019 using data from PubMed, MeSH and CancerIndex

Mutated Genes and Abnormal Protein Expression (100)

How to use this data tableClicking on the Gene or Topic will take you to a separate more detailed page. Sort this list by clicking on a column heading e.g. 'Gene' or 'Topic'.

GeneLocationAliasesNotesTopicPapers
EWSR1 22q12.2 EWS, EWS-FLI1, bK984G1.4 -EWSR1 and Soft Tissue Sarcoma
356
CD34 1q32.2 -CD34 and Soft Tissue Sarcoma
212
KIT 4q12 PBT, SCFR, C-Kit, CD117 -KIT and Soft Tissue Sarcoma
208
PTEN 10q23.31 BZS, DEC, CWS1, GLM2, MHAM, TEP1, MMAC1, PTEN1, 10q23del -PTEN and Soft Tissue Sarcoma
83
BCOR Xp11.4 MAA2, ANOP2, MCOPS2 -BCOR and Soft Tissue Sarcoma
71
SMARCB1 22q11.23 RDT, CSS3, INI1, SNF5, Snr1, BAF47, MRD15, RTPS1, Sfh1p, hSNFS, SNF5L1, SWNTS1, PPP1R144 -SMARCB1 and Soft Tissue Sarcoma
70
DDIT3 12q13.3 CHOP, CEBPZ, CHOP10, CHOP-10, GADD153 Translocation
-t(12;16)(q13;p11) FUS-DDIT3 in Mixoid Liposarcoma
-DDIT3 and Soft Tissue Cancers
39
AKT1 14q32.33 AKT, PKB, RAC, CWS6, PRKBA, PKB-ALPHA, RAC-ALPHA -AKT1 and Sarcoma
53
PDGFRB 5q32 IMF1, KOGS, IBGC4, JTK12, PDGFR, PENTT, CD140B, PDGFR1, PDGFR-1 -PDGFRB and Soft Tissue Sarcoma
46
CD99 Xp22.33 and Yp11.2 MIC2, HBA71, MIC2X, MIC2Y, MSK5X -CD99 and Soft Tissue Cancers
43
SLC2A1 1p34.2 CSE, PED, DYT9, GLUT, DYT17, DYT18, EIG12, GLUT1, HTLVR, GLUT-1, SDCHCN, GLUT1DS -GLUT1 expression in Soft Tissue Sarcoma
42
PIK3CA 3q26.32 MCM, CWS5, MCAP, PI3K, CLOVE, MCMTC, PI3K-alpha, p110-alpha -PIK3CA and Soft Tissue Sarcoma
42
FUS 16p11.2 TLS, ALS6, ETM4, FUS1, POMP75, HNRNPP2 Translocation
-t(12;16)(q13;p11) FUS-DDIT3 in Mixoid Liposarcoma
-t(7;16)(q33;p11) FUS-CREB3L2 in Low-grade fibromyxoid sarcoma
39
JAZF1 7p15.2-p15.1 TIP27, ZNF802 -JAZF1 and Soft Tissue Sarcoma
38
PAX3 2q35 WS1, WS3, CDHS, HUP2 -PAX3 and Soft Tissue Cancers
36
ATF1 12q13.12 TREB36, EWS-ATF1, FUS/ATF-1 -ATF1 and Soft Tissue Cancers
32
MSH2 2p21 FCC1, COCA1, HNPCC, LCFS2, HNPCC1 -MSH2 and Soft Tissue Sarcoma
28
TOP1 20q12 TOPI -TOP1 and Soft Tissue Sarcoma
27
MYOG 1q32.1 MYF4, myf-4, bHLHc3 -MYOG and Soft Tissue Sarcoma
25
MDM4 1q32.1 HDMX, MDMX, MRP1 -MDM4 and Soft Tissue Sarcoma
24
PAX7 1p36.13 HUP1, RMS2, PAX7B -PAX7 and Soft Tissue Cancers
23
NKX2-2 20p11.22 NKX2B, NKX2.2 -NKX2-2 and Soft Tissue Sarcoma
18
ERG 21q22.2 p55, erg-3 -ERG and Soft Tissue Cancers
17
ETV6 12p13.2 TEL, THC5, TEL/ABL -ETV6 and Soft Tissue Cancers
17
NR4A3 9q31.1 CHN, TEC, CSMF, NOR1, MINOR -NR4A3 and Soft Tissue Cancers
16
MYB 6q23.3 efg, Cmyb, c-myb, c-myb_CDS -MYB and Soft Tissue Sarcoma
16
MET 7q31.2 HGFR, AUTS9, RCCP2, c-Met, DFNB97 -C-MET and Soft Tissue Cancers
16
TSPAN31 12q13.3 SAS -TSPAN31 and Soft Tissue Sarcoma
15
CREB3L2 7q33 BBF2H7 Translocation
-t(7;16)(q33;p11) FUS-CREB3L2 in Low-grade fibromyxoid sarcoma
-CREB3L2 and Soft Tissue Cancers
14
MYOD1 11p15.1 PUM, MYF3, MYOD, bHLHc1 -MYOD1 and Soft Tissue Cancers
14
CIC 19q13.2 -CIC and Soft Tissue Cancers
12
DUX4L1 4q35.2 DUX4, DUX10 -DUX4 and Soft Tissue Cancers
11
PTER 10p13 HPHRP, RPR-1 -PTER and Soft Tissue Cancers
11
S100A6 1q21.3 2A9, PRA, 5B10, CABP, CACY, S10A6 -S100A6 and Soft Tissue Sarcoma
10
MUC4 3q29 ASGP, MUC-4, HSA276359 -MUC4 and Soft Tissue Cancers
10
CREB1 2q34 CREB -CREB1 and Soft Tissue Cancers
9
CTAG1B Xq28 CTAG, ESO1, CT6.1, CTAG1, LAGE-2, LAGE2B, NY-ESO-1 -CTAG1B and Soft Tissue Sarcoma
9
TGFBR3 1p22.1 BGCAN, betaglycan -TGFBR3 and Soft Tissue Cancers
9
ASPSCR1 17q25.3 TUG, ASPL, ASPS, RCC17, UBXD9, UBXN9, ASPCR1 Translocation
-der(17)t(X;17)(p11.2;q25) in Alveolar Soft-Part Sarcoma
-ASPSCR1 and Soft Tissue Cancers
8
TFG 3q12.2 TF6, HMSNP, SPG57, TRKT3 -TFG and Soft Tissue Sarcoma
8
OSCAR 19q13.42 PIGR3, PIgR-3 -OSCAR and Soft Tissue Sarcoma
8
TCF12 15q21.3 HEB, CRS3, HTF4, TCF-12, bHLHb20, HsT17266 -TCF12 and Soft Tissue Sarcoma
8
GNAS 20q13.32 AHO, GSA, GSP, POH, GPSA, NESP, SCG6, SgVI, GNAS1, PITA3, C20orf45 -GNAS and Soft Tissue Cancers
8
HMGA1 6p21.31 HMG-R, HMGIY, HMGA1A -HMGA1 and Soft Tissue Cancers
7
CREB3L1 11p11.2 OASIS -CREB3L1 and Soft Tissue Cancers
7
CYP3A4 7q22.1 HLP, CP33, CP34, CYP3A, NF-25, CYP3A3, P450C3, CYPIIIA3, CYPIIIA4, P450PCN1 -CYP3A4 and Soft Tissue Sarcoma
6
CKAP4 12q23.3 p63, CLIMP-63, ERGIC-63 -CKAP4 and Soft Tissue Sarcoma
6
NCOA2 8q13.3 SRC2, TIF2, GRIP1, KAT13C, NCoA-2, bHLHe75 -NCOA2 and Soft Tissue Cancers
6
CYP3A5 7q22.1 CP35, PCN3, CYPIIIA5, P450PCN3 -CYP3A5 and Soft Tissue Sarcoma
6
YEATS4 12q15 YAF9, GAS41, NUBI-1, 4930573H17Rik, B230215M10Rik -YEATS4 and Soft Tissue Sarcoma
6
CD163 12p13.3 M130, MM130 -CD163 and Soft Tissue Sarcoma
6
MAGEA3 Xq28 HIP8, HYPD, CT1.3, MAGE3, MAGEA6 -MAGEA3 and Soft Tissue Sarcoma
6
FLT4 5q35.3 PCL, FLT-4, FLT41, LMPH1A, VEGFR3, VEGFR-3 -FLT4 and Soft Tissue Sarcoma
6
LATS1 6q25.1 wts, WARTS -LATS1 and Soft Tissue Sarcoma
6
MGEA5 10q24.32 OGA, MEA5, NCOAT -MGEA5 and Soft Tissue Cancers
5
TLE1 9q21.32 ESG, ESG1, GRG1 -TLE1 and Soft Tissue Cancers
5
DAPK2 15q22.31 DRP1, DRP-1 -DAPK2 and Soft Tissue Cancers
4
TAF15 17q12 Npl3, RBP56, TAF2N, TAFII68 -TAF15 and Soft Tissue Cancers
4
PTPRD 9p24.1-p23 HPTP, PTPD, HPTPD, HPTPDELTA, RPTPDELTA -PTPRD and Soft Tissue Sarcoma
4
MED12 Xq13.1 OKS, FGS1, HOPA, OPA1, OHDOX, ARC240, CAGH45, MED12S, TNRC11, TRAP230 -MED12 and Soft Tissue Cancers
4
EZH2 7q36.1 WVS, ENX1, EZH1, KMT6, WVS2, ENX-1, EZH2b, KMT6A -EZH2 and Soft Tissue Cancers
4
TOP2A 17q21.2 TOP2, TP2A -TOP2A and Soft Tissue Sarcoma
4
PATZ1 22q12.2 ZSG, MAZR, PATZ, RIAZ, ZBTB19, ZNF278, dJ400N23 -PATZ1 and Soft Tissue Sarcoma
4
LMNA 1q22 FPL, IDC, LFP, CDDC, EMD2, FPLD, HGPS, LDP1, LMN1, LMNC, MADA, PRO1, CDCD1, CMD1A, FPLD2, LMNL1, CMT2B1, LGMD1B -LMNA and Soft Tissue Cancers
3
CD1A 1q23.1 R4, T6, CD1, FCB6, HTA1 -CD1A and Soft Tissue Sarcoma
3
CAMTA1 1p36.31-p36.23 CANPMR -CAMTA1 and Soft Tissue Cancers
3
WWTR1 3q25.1 TAZ -WWTR1 and Soft Tissue Cancers
3
COL1A1 17q21.33 OI1, OI2, OI3, OI4, EDSC -COL1A1 and Soft Tissue Cancers
3
NNAT 20q11.23 Peg5 -NNAT and Soft Tissue Sarcoma
3
GAPDH 12p13.31 G3PD, GAPD, HEL-S-162eP -GAPDH and Soft Tissue Cancers
3
MIF 22q11.23 GIF, GLIF, MMIF -MIF and Soft Tissue Cancers
2
DAPK1 9q21.33 DAPK -DAPK1 and Soft Tissue Cancers
2
CDKN1B 12p13.1 KIP1, MEN4, CDKN4, MEN1B, P27KIP1 Prognostic
-CDKN1B Expression and Survival in Liposarcoma
2
SRSF3 6p21.31-p21.2 SFRS3, SRp20 -SRSF3 and Soft Tissue Sarcoma
2
TIMP3 22q12.3 SFD, K222, K222TA2, HSMRK222 -TIMP3 and Soft Tissue Cancers
2
ATF6 1q23.3 ACHM7, ATF6A -ATF6 and Soft Tissue Sarcoma
2
SSTR1 14q21.1 SS1R, SS1-R, SRIF-2, SS-1-R -SSTR1 and Soft Tissue Cancers
2
TUSC2 3p21.31 PAP, FUS1, PDAP2, C3orf11 -TUSC2 and Soft Tissue Sarcoma
2
RANBP2 2q12.3 ANE1, TRP1, TRP2, ADANE, IIAE3, NUP358 -RANBP2 and Soft Tissue Sarcoma
2
PTPRC 1q31.3-q32.1 LCA, LY5, B220, CD45, L-CA, T200, CD45R, GP180 -PTPRC and Soft Tissue Sarcoma
2
ICAM1 19p13.2 BB2, CD54, P3.58 -ICAM1 and Soft Tissue Cancers
2
MAP2K4 17p12 JNKK, MEK4, MKK4, SEK1, SKK1, JNKK1, SERK1, MAPKK4, PRKMK4, SAPKK1, SAPKK-1 -MAP2K4 and Soft Tissue Cancers
2
TPTE 21p11.2 CT44, PTEN2 -TPTE and Soft Tissue Cancers
2
MMP9 20q13.12 GELB, CLG4B, MMP-9, MANDP2 -MMP9 and Soft Tissue Cancers
2
FHIT 3p14.2 FRA3B, AP3Aase -FHIT and Soft Tissue Cancers
2
GSTA1 6p12.2 GST2, GTH1, GSTA1-1, GST-epsilon -GSTA1 and Soft Tissue Sarcoma
2
AREG 4q13.3 AR, SDGF, AREGB, CRDGF -AREG and Soft Tissue Cancers
1
FOXL2 3q22.3 BPES, PFRK, POF3, BPES1, PINTO -FOXL2 and Soft Tissue Sarcoma
1
ACVRL1 12q13.13 HHT, ALK1, HHT2, ORW2, SKR3, ALK-1, TSR-I, ACVRLK1 -ACVRL1 and Soft Tissue Cancers
1
PTPRF 1p34.2 LAR, BNAH2 -PTPRF and Soft Tissue Sarcoma
1
FGF23 12p13.32 ADHR, FGFN, HYPF, HPDR2, PHPTC -FGF23 and Soft Tissue Cancers
1
ANO1 11q13.3 DOG1, TAOS2, ORAOV2, TMEM16A -ANO1 and Soft Tissue Cancers
1
CHIA 1p13.2 CHIT2, AMCASE, TSA1902 -CHIA and Soft Tissue Cancers
1
IL2RB 22q12.3 CD122, IMD63, IL15RB, P70-75 -IL2RB and Soft Tissue Cancers
1
LDHA 11p15.1 LDHM, GSD11, PIG19, HEL-S-133P -LDHA and Soft Tissue Cancers
1
SSX1 Xp11.23 SSRC, CT5.1 Translocation
-t(X;18)(p11.2;q11.2) SS18-SSX1 in Synovial Sarcoma
TFE3 Xp11.23 TFEA, RCCP2, RCCX1, bHLHe33 Translocation
-der(17)t(X;17)(p11.2;q25) in Alveolar Soft-Part Sarcoma
SSX2 Xp11.22 SSX, HD21, CT5.2, CT5.2A, HOM-MEL-40 Translocation
-t(X;18)(p11.2;q11.2) SS18-SSX2 in Synovial Sarcoma
SSX4 Xp11.23 CT5.4 Translocation
-t(X;18)(p11.2;q11.2) SS18-SSX4 in Synovial Sarcoma
SS18 18q11.2 SYT, SSXT Translocation
-t(X;18)(p11.2;q11.2) SS18-SSX1 in Synovial Sarcoma
-t(X;18)(p11.2;q11.2) SS18-SSX2 in Synovial Sarcoma
-t(X;18)(p11.2;q11.2) SS18-SSX4 in Synovial Sarcoma

Note: list is not exhaustive. Number of papers are based on searches of PubMed (click on topic title for arbitrary criteria used).

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Cite this page: Cotterill SJ. Soft Tissue Sarcoma, Cancer Genetics Web: http://www.cancer-genetics.org/X2003.htm Accessed:

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