| MC2R | 18p11.21 | ACTHR | | -Adrenocortical Cancer
-Testicular Cancer
|
| RALBP1 | 18p11.22 | RIP1, RLIP1, RLIP76 | | -Colorectal Cancer
-Liver Cancer
-Lung Cancer
-Lung Cancer, Non-Small Cell
-Pancreatic Cancer
-Prostate Cancer
|
| EPB41L3 | 18p11.31 | 4.1B, DAL1, DAL-1 | | -Breast Cancer
-Cervical Cancer
-Lung Cancer
-Lung Cancer, Non-Small Cell
|
| TYMS | 18p11.32 | TS, TMS, HST422 | | -Acute Lymphocytic Leukaemia (ALL)
-Breast Cancer
-Colorectal Cancer
-Lung Cancer
-Lung Cancer, Non-Small Cell
-Stomach Cancer
|
| ADCYAP1 | 18p11.32 | PACAP | | -Pituitary Tumors
|
| YES1 | 18p11.32 | Yes, c-yes, HsT441, P61-YES | | -Breast Cancer
-Colorectal Cancer
-Liver Cancer
-Melanoma
|
| ROCK1 | 18q11.1 | ROCK-I, P160ROCK | | -Bone Cancer (primary)
-Breast Cancer
-Colorectal Cancer
-Lung Cancer
-Prostate Cancer
-Stomach Cancer
|
| MIB1 | 18q11.2 | MIB, DIP1, ZZZ6, DIP-1, LVNC7, ZZANK2 | | -Brain Tumours, Childhood
-Breast Cancer
-Cervical Cancer
-Pheochromocytoma and Paraganglioma
-Prostate Cancer
-Salivary Gland Cancer
-Skin Cancer
-Stomach Cancer
-Testicular Cancer
|
| IMPACT | 18q11.2-q12.1 | RWDD5 | | |
| RBBP8 | 18q11.2 | RIM, COM1, CTIP, JWDS, SAE2, SCKL2 | | -Breast Cancer
-Ovarian Cancer
|
| GATA6 | 18q11.2 | | | -Adrenocortical Cancer
-Lung Cancer
-Ovarian Cancer
-Pancreatic Cancer
-Rectal Cancer
-Stomach Cancer
|
| SS18 | 18q11.2 | SYT, SSXT | Somatic
Translocation | -Synovial Sarcoma
|
| ZNF521 | 18q11.2 | EHZF, Evi3 | Somatic | -Acute Lymphocytic Leukaemia (ALL)
-Medulloblastoma
-Pancreatic Cancer
|
| CDH2 | 18q12.1 | CDHN, NCAD, CD325, CDw325 | | -Breast Cancer
-Cervical Cancer
-Liver Cancer
-Lung Cancer
-Lung Cancer, Non-Small Cell
-Prostate Cancer
-Testicular Cancer
|
| MBD1 | 18q21.1 | RFT, PCM1, CXXC3 | | -Breast Cancer
-Colorectal Cancer
-Lung Cancer
-Lung Cancer, Non-Small Cell
-Pancreatic Cancer
-Prostate Cancer
|
| SMAD7 | 18q21.1 | CRCS3, MADH7, MADH8 | | -Breast Cancer
-Colorectal Cancer
-Pancreatic Cancer
-Stomach Cancer
-Uterine Sarcoma
|
| SMAD2 | 18q21.1 | JV18, MADH2, MADR2, JV18-1, hMAD-2, hSMAD2 | | -Bladder Cancer
-Breast Cancer
-Colorectal Cancer
-Eye Cancer
-Lung Cancer
-Pancreatic Cancer
-Uterine Sarcoma
|
| DCC | 18q21.2 | CRC18, CRCR1, MRMV1, IGDCC1, NTN1R1 | | -Colorectal Cancer
-Stomach Cancer
-Testicular Cancer
|
| POLI | 18q21.2 | RAD30B, RAD3OB | | -Acute Myeloid Leukaemia
-Bladder Cancer
-Brain Tumours, Childhood
-Breast Cancer
-Cervical Cancer
-Chronic Lymphocytic Leukemia
-Lung Cancer
-Thyroid Cancer
|
| TCF4 | 18q21.2 | E2-2, ITF2, PTHS, SEF2, FECD3, ITF-2, SEF-2, TCF-4, SEF2-1, SEF2-1A, SEF2-1B, SEF2-1D, bHLHb19 | | -Breast Cancer
-Colorectal Cancer
-Liver Cancer
|
| SMAD4 | 18q21.2 | JIP, DPC4, MADH4, MYHRS | Germline & Somatic | -Adenomatous Polyposis Coli
-Breast Cancer
-Cervical Cancer
-Colorectal Cancer
-Liver Cancer
-Lung Cancer
-Pancreatic Cancer
-Stomach Cancer
|
| MBD2 | 18q21.2 | DMTase, NY-CO-41 | | -Bladder Cancer
-Breast Cancer
-Lung Cancer
-Prostate Cancer
-Stomach Cancer
-Uterine Sarcoma
|
| MIR122 | 18q21.31 | MIR122A, MIRN122, mir-122, MIRN122A, miRNA122, miRNA122A, hsa-mir-122 | | -Colorectal Cancer
-Liver Cancer
-Osteosarcoma
-Prostate Cancer
|
| MALT1 | 18q21.32 | MLT, MLT1, IMD12, PCASP1 | Somatic
Translocation | -MALT Lymphoma
-Lung Cancer
-Skin Cancer
-Stomach Cancer
|
| SERPINB2 | 18q21.33-q22.1 | PAI, PAI2, PAI-2, PLANH2, HsT1201 | | -Acute Myeloid Leukaemia
-Bone Cancer (primary)
-Breast Cancer
-Lung Cancer
-Prostate Cancer
|
| PHLPP1 | 18q21.33 | SCOP, PHLPP, PPM3A, PLEKHE1 | | -Prostate Cancer
|
| SERPINB5 | 18q21.33 | PI5, maspin | | -Breast Cancer
-Lung Cancer
-Ovarian Cancer
-Prostate Cancer
-Stomach Cancer
|
| TNFRSF11A | 18q21.33 | FEO, OFE, ODFR, OSTS, PDB2, RANK, CD265, OPTB7, TRANCER, LOH18CR1 | | -Breast Cancer
-Lung Cancer
-Multiple Myeloma
-Osteosarcoma
-Prostate Cancer
|
| KDSR | 18q21.33 | DHSR, FVT1, SDR35C1 | Somatic | |
| BCL2 | 18q21.33 | Bcl-2, PPP1R50 | Somatic
Translocation | -MALT Lymphoma
-Acute Lymphocytic Leukaemia (ALL)
-Breast Cancer
-Cervical Cancer
-Lung Cancer
-Small Cell Lung Cancer
-Non-Hodgkin Lymphoma
-Oral Cavity Cancer
-Osteosarcoma
-Salivary Gland Cancer
-Uterine Sarcoma
|
| NFATC1 | 18q23 | NFAT2, NFATc, NF-ATC, NF-ATc1.2 | Somatic
Translocation | -Bone Cancer (primary)
-Breast Cancer
-Multiple Myeloma
-Ovarian Cancer
-Pancreatic Cancer
|
Click on the gene name for detailed information. Type in the Search box e.g. 'germline' or 'Breast Cancer' to search within Chromosome 18; or Sort by clicking on a column heading e.g. 'Gene'.
Chromosome 18 (Phenotype entries)